Template-Type: ReDIF-Article 1.0 Author-Name: J.V.S. Rauthan Author-Workplace-Name: Fisheries Research Lab, Department of Zoology, D.A.V. (P.G.) College, Dehradun, Uttarakhand-248001, India Author-Name: M.K. Purohit Author-Workplace-Name: Department of Zoology, S.G.R.R. (P.G.) College, Dehradun, Uttarakhand-248001, India Author-Name: Sundar Singh Author-Workplace-Name: Fisheries Research Lab, Department of Zoology, D.A.V. (P.G.) College, Dehradun, Uttarakhand-248001, India Title: Haematological and Biochemical Changes in Freshwater Zig-Zag Eel Mastacembelus armatus (Lacepede) Infected with Trypanosomes Abstract: Trypanosome is widespread parasite in freshwater fishes causing disease Trypanosomiasis. During the present investigation, 20% of sample population Mastacembelus armatus from song river system of Dehradun (Uttarakhand) showed trypanosome infection. The presence of trypanosomes in the blood caused conspicuous changes in TEC, TLC, Hb, ESR, PCV, MCV, MCH, MCHC and DLC correlated with the intensity of infection. In general, anaemia accompanied with erthropenia, microcytosis, macrocytosis and basophilia. The severe infection resulted decrease is alkaline phosphate, acid phosphate, serum cholesterol, blood urea, serum, iron and lactate dehydrogenase, aldose, and S-nuclectidase increased. Keywords: Haematology, Biochemicals, Trypanosomes, Mastacembelus armatus Journal: Inventum Biologicum: An International Journal of Biological Research Pages: 121-125 Volume: 2 Issue: 4 Year: 2022 File-URL: https://journals.worldbiologica.com/ib/article/view/41 File-Format: text/html File-URL: https://journals.worldbiologica.com/ib/article/view/41/89 File-Format: Application/pdf Handle: RePEc:adg:ibijbr:v:2:y:2022:i:4:p:121-125