Template-Type: ReDIF-Article 1.0
Author-Name: Anjana Suresh
Author-Workplace-Name: Department of Microbiology, Centre for Marine Science and Technology (CMST), Rajakkamangalam, Manonmanium Sundarnar University, Tirunelveli, Tamilnadu, India
Title:  Helicobacter pylori Induced Neurological Disease and Therapy
Abstract:  About 50% of people worldwide are infected with the gut pathogen Helicobacter pylori. The chance of developing gastric cancer and duodenal and stomach ulcer disease is greatly increased by H. pylori infection, which also causes chronic inflammation. An H. pylori infection typically induces alterations to the gut bacteria and a prolonged inflammatory response, other than from the immediate release of several inflammatory substances, such as chemokines, growth-regulated oncogene, and cytokines. which can be ingested and have an effect throughout the body. If detectable levels of inflammatory mediators remain at both the systemic and local levels, the gut-brain axis or blood-brain barrier will probably to become altered. These proinflammatory factors can cause ischemic stroke, multiple sclerosis, Devic syndrome, Guillain-Barre syndrome, Bickerstaff brainstem encephalitis, Alzheimer's disease, and migraines. They can also cause brain inflammation and the loss of neurons.  Included in this overview are the neurological diseases caused by H. pylori, their eradication, and customized treatments.
Keywords: Gut pathogen, Helicobacter pylori, Inflammatory mediators, Neurological disease
Journal: Inventum Biologicum: An International Journal of Biological Research
Pages: 5-17
Volume: 3
Issue: 1
Year: 2023
File-URL: https://journals.worldbiologica.com/ib/article/view/30
File-Format: text/html
File-URL: https://journals.worldbiologica.com/ib/article/view/30/93
File-Format: Application/pdf
Handle: RePEc:adg:ibijbr:v:3:y:2023:i:1:p:5-17